{"id":1377,"date":"2018-09-12T00:00:00","date_gmt":"2018-09-12T00:00:00","guid":{"rendered":"https:\/\/www.aboutskinderm.com\/experimental-blood-test-to-detect-melanoma\/"},"modified":"2024-04-27T02:10:08","modified_gmt":"2024-04-27T02:10:08","slug":"experimental-blood-test-to-detect-melanoma","status":"publish","type":"post","link":"https:\/\/www.aboutskinderm.com\/experimental-blood-test-to-detect-melanoma\/","title":{"rendered":"Experimental Blood Test to Detect Melanoma"},"content":{"rendered":"<p id=\"\">Australian researchers have developed a blood test that is capable of detecting melanoma in its early stages. &nbsp;This diagnostic test detects antibodies in the blood, with significant accuracy, to identify patients with primary melanoma. &nbsp;Antibodies are very specific proteins made by a person\u2019s immune system to fight off foreign substances such as bacteria, viruses, toxins as well as cancer cells. &nbsp;The research team has identified a combination of 10 antibodies that best signal the presence of melanoma. The researchers were able to identify people with melanoma with 84% accuracy (16% false positive rate), in a study with 245 total blood samples (with 124 samples from melanoma patients compared to 121 samples from healthy patients). &nbsp;The blood samples were drawn within 1-3 months of initial primary melanoma diagnosis. &nbsp;However, in order for the test to be more clinically useful, researchers do plan to perform a larger clinical trial to refine the test, hoping to increase the accuracy to 90% or greater.<\/p>\n<p id=\"\">The study was published in the July 17, 2018 edition of <a href=\"http:\/\/www.oncotarget.com\/index.php?journal=oncotarget&#038;page=article&#038;op=view&#038;path%5B%5D=25669\" target=\"_blank\" rel=\"noopener\">Oncotarget<\/a>.<\/p>\n<p id=\"\"><em id=\"\">Dr. Ho\u2019s Commentary:<\/em> &nbsp;Having a new diagnostic test to detect cancer such as melanoma is always exciting and welcomed. &nbsp;Early diagnosis is extremely important for melanoma since when detected early, the 5-year survival rate can be over 95%, but with advanced metastatic disease the corresponding survival rate drops below 20%. &nbsp;Nonetheless, more studies will be needed to verify how accurate this test is and how it would be best used in daily clinical practice. &nbsp;The question of which patients are appropriate to make this test worthwhile and financially feasible is yet to be answered. &nbsp;The test, of course, does not tell us the location of the tumor, thus a biopsy of clinically suspicious skin lesion(s) would still be required. &nbsp;The test also needs to be as accurate as possible otherwise patients with false-positive results might receive unnecessary follow up evaluation.<\/p>\n<p id=\"\">\n<p id=\"\">For now, the best screening strategies are still regular self skin examinations at home and a regularly scheduled professional exam by a board-certified dermatologist.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Australian researchers have developed a blood test that is capable of detecting melanoma in its early stages. This diagnostic<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[71],"tags":[],"class_list":["post-1377","post","type-post","status-publish","format-standard","hentry","category-blog"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Experimental Blood Test to Detect Melanoma - AboutSkin Dermatology and DermSurgery, PC. - Denver Dermatologist<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.aboutskinderm.com\/experimental-blood-test-to-detect-melanoma\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Experimental Blood Test to Detect Melanoma - AboutSkin Dermatology and DermSurgery, PC. - Denver Dermatologist\" \/>\n<meta property=\"og:description\" content=\"Australian researchers have developed a blood test that is capable of detecting melanoma in its early stages. 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